About Us

PMI-BabyWho We Are

Biocoat, Inc. is a manufacturer of coating reagents and a research facility dedicated to innovation, accuracy and our clients. At our state-of-the-art, FDA registered facility in Horsham PA, we manufacture two fertility products, the HBA® Slide and the PICSI® Dish. These are manufactured in a controlled, clean room environment, then shipped to fertility clinics worldwide by our distributor ORIGIO Inc., a Cooper Surgical Company.

Over 14 years ago we began collaborating with Yale University School of Medicine, building on their basic discovery of a simple binding test for determining sperm maturity. From this research, we developed a sperm binding assay, HBA® Slide, and a sperm selection device, PICSI® Dish, used in Intracytoplasmic Sperm Injection (ICSI). Both of these are based on the ability of mature sperm to bind to Hyaluronan (HA).

Our goal, on the Reproductive Technology side of Biocoat Inc., is to assist Reproductive Endocrinologists, Urologists, OB/GYN’s and Fertility Clinics all over the country and the world with their mission. The mission to help you expand your family!


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The Science
HBA® Assay [ View HBA Product Information Sheet ]

PICSI® Dish [ View PICSI Product Information Sheet ]

Worrilow Paper [ View Worrilow Paper ]


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PMI-HandsReduces Pregnancy Loss Rate!

A recent study compared sperm selected via hyaluronan-binding to normally motile sperm in ICSI patients where male factor/low HA binding scores were present. Couples who received the PICSI-selected sperm were more likely to get pregnant compared to their counterparts. More importantly, among the control (non-PICSI) patients, 15% of the pregnancies (detected by the presence of a fetal sac) never developed a fetal heart beat. Among the PICSI group, none of the pregnancies detected by the presence of a fetal sac were lost – all of them developed a fetal heart beat. This remarkable reduction in the loss of pregnancy accounts in part for the improved overall pregnancy rate seen in the PICSI group.

Worrilow et al. (2013) found that a combination of the diagnostic abilities of the HBA® Slide and the HA-sperm selection abilities of the PICSI® Dish improved Clinical Pregnancy Rate and significantly reduced Pregnancy Loss Rate in ICSI patients diagnosed with low HBA® Scores (≤65% binding ratio). This study also demonstrated that 15% of all ICSI patients have a low HBA Score (≤65%) and would benefit from HA sperm diagnostics and selection. Worrilow Paper [ View Worrilow Paper ].


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Get Them Involved!

PMI-ClipBoardGetting your Fertility Specialist Onboard!

In order to get your Fertility Specialist informed and using the HBA® Slide and the PICSI® Sperm Selection Device, we have created an Offer that will allow them to get these products in hand so you can benefit as soon as possible. We are offering Fertility Specialists the opportunity to receive both products at a favorable cost initially, or a Free Trial Offer, if applicable.

Please click the Discount Certificate button to view the special Discount Certificate. Download the PDF, email it to your Fertility Specialist, or print it out and hand deliver it.

You may request they use HBA® and PICSI® for your semen analysis and or ICSI procedure right away!

* “Free Trial Offer for first time customers only.”


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